Supposedly, there was going to be another LoK game called "The Dark Prophecy" or something, but then, like Shenmue III[1], it didn't get made.
From Wikipedia (http://en.wikipedia.org/wiki/Legacy_of_Kain), regarding the future of the series:
The fifth and most recent game in the series "started life as Soul Reaver 3", but the developers decided to take the game in a new direction, uniting elements of the two sub-series into one game with re-vamped game systems. They picked the title Legacy of Kain: Defiance to reflect the new focus. However, Defiance did not meet Eidos' sales expectations, and this, combined with the exit of two key Crystal Dynamics staff members (director/writer Amy Hennig and game designer Richard Lemarchand) shortly after the release of Defiance sparked fan speculation that it would become the last Legacy of Kain game. The deaths of voice actor Tony Jay and Crystal Dynamics employee Kyle Mannerberg were regarded as further setbacks. Nonetheless, there are signs that Crystal Dynamics has not forgotten Legacy of Kain in the form of easter eggs in Tomb Raider: Legend, and statements from Eidos US CEO Bill Gardner expressing interest in reviving the Legacy of Kain series.
Development was started (in 2004) on a sixth game in the series, titled ‘Legacy of Kain: The Dark Prophecy’. This may have been a continuation of the story after the events portrayed in Defiance. PlayStation 2 development was underway for at least 3 months before the project was canceled. The future of the series is unknown at this point.
Sadly, even if they do make another LoK game at some point, it will probably be BO2 quality or worse, in which case they may as well not even bother.
[1] - The fate of the Shenmue series is something I could rant about forever. Hopefully, the appearance of Ryo Hazuki in that Sonic and SEGA All-Stars Racing (http://www.youtube.com/watch?v=jILxmTzZd5Q)[2] thing might lead to... something, but I'm not going to hold my breath for a second.
[2] - Man, that music (http://www.youtube.com/watch?v=ozSwIMz9v9o&fmt=18) at the beginning of that clip (before it changed to that crappy "generic race music") almost brings a tear to my eye. Shenmue always had some (http://www.youtube.com/watch?v=Z1JTWXCHUb4&fmt=18) of (http://www.youtube.com/watch?v=_1fyEAAmY2Y&fmt=18) the (http://www.youtube.com/watch?v=krk-1PnvpFI&fmt=18) best (http://www.youtube.com/watch?v=Dp-U3ZTEer0&fmt=18) music (http://www.youtube.com/view_play_list?p=2A8D4A97B01DAD45&page=1). God dammit, now I want to play Shenmue again... except I also kind of don't, because the second game ends on such a crazy cliffhanger and it'll get me all depressed again. How the hell did I end up talking about Shenmue instead of Legacy of Kain here? o_O
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From Wikipedia (http://en.wikipedia.org/wiki/Legacy_of_Kain), regarding the future of the series:
The fifth and most recent game in the series "started life as Soul Reaver 3", but the developers decided to take the game in a new direction, uniting elements of the two sub-series into one game with re-vamped game systems. They picked the title Legacy of Kain: Defiance to reflect the new focus. However, Defiance did not meet Eidos' sales expectations, and this, combined with the exit of two key Crystal Dynamics staff members (director/writer Amy Hennig and game designer Richard Lemarchand) shortly after the release of Defiance sparked fan speculation that it would become the last Legacy of Kain game. The deaths of voice actor Tony Jay and Crystal Dynamics employee Kyle Mannerberg were regarded as further setbacks. Nonetheless, there are signs that Crystal Dynamics has not forgotten Legacy of Kain in the form of easter eggs in Tomb Raider: Legend, and statements from Eidos US CEO Bill Gardner expressing interest in reviving the Legacy of Kain series.
Development was started (in 2004) on a sixth game in the series, titled ‘Legacy of Kain: The Dark Prophecy’. This may have been a continuation of the story after the events portrayed in Defiance. PlayStation 2 development was underway for at least 3 months before the project was canceled. The future of the series is unknown at this point.
Sadly, even if they do make another LoK game at some point, it will probably be BO2 quality or worse, in which case they may as well not even bother.
[1] - The fate of the Shenmue series is something I could rant about forever. Hopefully, the appearance of Ryo Hazuki in that Sonic and SEGA All-Stars Racing (http://www.youtube.com/watch?v=jILxmTzZd5Q)[2] thing might lead to... something, but I'm not going to hold my breath for a second.
[2] - Man, that music (http://www.youtube.com/watch?v=ozSwIMz9v9o&fmt=18) at the beginning of that clip (before it changed to that crappy "generic race music") almost brings a tear to my eye. Shenmue always had some (http://www.youtube.com/watch?v=Z1JTWXCHUb4&fmt=18) of (http://www.youtube.com/watch?v=_1fyEAAmY2Y&fmt=18) the (http://www.youtube.com/watch?v=krk-1PnvpFI&fmt=18) best (http://www.youtube.com/watch?v=Dp-U3ZTEer0&fmt=18) music (http://www.youtube.com/view_play_list?p=2A8D4A97B01DAD45&page=1). God dammit, now I want to play Shenmue again... except I also kind of don't, because the second game ends on such a crazy cliffhanger and it'll get me all depressed again. How the hell did I end up talking about Shenmue instead of Legacy of Kain here? o_O